Quantitative label-free RNA detection using surface-enhanced Raman spectroscopy.

Probing biomolecular interactions using surface enhanced Raman spectroscopy: label-free protein detection using a G-quadruplex DNA aptamer.

We demonstrate a strategy for label-free protein detection through monitoring the Surface Enhanced Raman Spectrum of an aptamer probe attached to a gold nanoshell. Low limit of detection and minimal non-specific binding show potential for in vitro and in vivo assays.

Biosensing Based on Surface-Enhanced Raman Spectroscopy by Using Metal Nanoparticles

Surface-enhanced Raman spectroscopy (SERS) is a promising tool in the analytical science because it provides good selectivity and sensitivity without the labeling process required by fluorescence detection. This technique consists of locating the target analyte on nanometer range of roughed Au-nanoparticles. The presence of the metal nanoparticles provides a tremendous enhancement to the result...

Coating Of Silver Nanoparticles by Sputtering Method on Glass Substrates as Surface-Enhanced Raman Spectroscopy (SERS) Biosensor for Detection of Whey Protein

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Surface-enhanced Raman scattering: an emerging label-free detection and identification technique for proteins.

The detection and identification of biologically important molecules has critical importance in several fields such as medicine, biotechnology, and pharmacology. Surface-enhanced Raman scattering (SERS) is a powerful emerging vibrational spectroscopic technique that allows not only for the characterization, but also for the identification and detection of biomacromolecules in a very short time....

Label-Free Detection of Single-Base Mismatches in DNA by Surface-Enhanced Raman Spectroscopy**